Clinical Perspective End of Life Care for HIV Dr. Ann S tewart, Medical Director, Casey House
Obj ectives To review local data on end of life care for patients with HIV/ AIDS in Toronto To look at changing cause of death To discuss recent cases of admission for end of life care To look at strategies for end of life care planning www. caseyhouse.com
Presenter Disclosure • Dr. Ann Stewart • Employee of Casey House www. caseyhouse.com
www. caseyhouse.com
Deaths at Casey House 100.00% 90.00% 80.00% 70.00% 60.00% 50.00% Percentage of admissions 40.00% 30.00% 20.00% 10.00% 0.00% 1988 2010 2012 2014 www. caseyhouse.com
Casey House Chart Review, 2008 Average age of death 48 +/ - 2.4 years Average number of years living with HIV 14.6 +/ -7.6 Pre-HAART average age of death 39 +/ - 2.4 years Mean number of years of living with HIV pre-HAART 1.5 +/ - 0.2 Halman et al, 2013; To et al, 2011 www. caseyhouse.com
Cause of Death: Pre and Post HAART Deaths Post-HAART Deaths Pre-HAART (1988) (2006-2008) AIDS related deaths 19% 25% AIDS related deaths Non-AIDS related deaths 81% Non-AIDS related 75% deaths Mycobacterium Avium Non‐AIDS malignancy, liver Complex, Toxoplasmosis, disease, respiratory Pneumocystis Pneumonia, disease, organ failure Kaposi Sarcoma From To et al. CAHR 2011 www. caseyhouse.com
Mature patients Present in late forties and fifties On ARV therapy, suppressed Develop malignancy Do poorly on chemo and radiation May be well-supported by friends and family – may not have much of a plan S low decline, with many hospital interventions www. caseyhouse.com
Y oung patients Can present in their 20’s May have history of opioid use with inj ection, and/ or mental health issues Often unhoused with few personal connections Unable to tolerate regular medication regimes Develop multiple complications of immuno- suppression and infectious disease: MAC, C Diff, CMV , endocarditis S till die of the classic complications of AIDS www. caseyhouse.com
Next….. • Claire Kendall • Associate Professor, Department of Family Medicine, University of Ottawa • Greg Robinson • Physician and community activist from Toronto • Richard Harding • Reader in Palliative Care, King’s College London UK www. caseyhouse.com
Thanks OHTN Fellow presenters Terrific team at Casey House www. caseyhouse.com
Complexity Frequency Percentage Homeless: no home, shelter, with friends/family, on street 16 19.3% Psychiatric: more than 1 Axis 1 diagnosis 77 92.8% Medical: more than 2 medical co-morbidities 28 33.7% 7 patients (8.4%) experienced all three complexities Only 1 (1.2%) patient had no complexity From Halman et al 2013, chart review of all patients admitted in 2008 N= 83 www. caseyhouse.com
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