Chemspace RNA-targeted library Description RNAs participate in - PowerPoint PPT Presentation

Apr 30, 2023 •363 likes •426 views

Chemspace RNA-targeted library Description RNAs participate in more cell mechanisms than it has been thought before. Aside from transferring information from the DNA, this type of biomolecules appears to affect numerous cell processes: very

Chemspace RNA-targeted library
Description RNAs participate in more cell mechanisms than it has been thought before. Aside from transferring information from the DNA, this type of biomolecules appears to affect numerous cell processes: very small part of the transcripts actually codes proteins. Targeting RNA with small molecules was suggested after discovering “druggability” of the nucleic acids similar to that of proteins. The targeting could be aimed at cell processes in humans or blocking RNA functions in bacteria or viruses.
Selection Starting with Chemspace Screening collection, we focused on 15 binding motifs in different RNAs associated with bacterial and viral infections. • Both ligand ‐ and target ‐ based approach • Annotations to the target and docking score are available Library size : 4 572 in-stock compounds You can order full set or selected subset based on your criteria; all compounds are supplied as powders, solutions, or dry films. Please contact us at sales@chem-space.com for more information.
Chemspace Compound sets Discover our Fragment Libraries : General Fragments Fluorine and Heavy Fragments • • 3D-Shaped Fragments Selected Fragments • • Acid and Amine Fragments Singleton Fragments • • Covalent Fragments Saturated and Spiro Fragments • • All libraries’ names are clickable links. Visit www.chem-space.com/flyers to find more Chemspace presentations!
Chemspace Compound sets Discover our Screening compounds : ChEMBL analogs High QED compounds • • CNS-Focused library Phenotypic Screening set • • Covalent Modifiers PPI Modulators • • Drug Impurities Pre-Plated compounds • • Drug Repurposing RNA-Targeted library • • Framework-Derived set Virtual Screening set • • All libraries’ names are clickable links. Visit www.chem-space.com/flyers to find more Chemspace presentations!
Thank You! The Chemspace Team

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