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Can Community Health Workers improve lives? Hope pervades HIV community Yet, there are many hurdles; South Africa Tx cascade. 24.7% tested for HIV & know results 83% linked to care vs. 41% in Eastern & Southern Africa 62% have


  1. Can Community Health Workers improve lives?

  2. Hope pervades HIV community

  3. Yet, there are many hurdles; South Africa Tx cascade. 24.7% tested for HIV & know results 83% linked to care vs. 41% in Eastern & Southern Africa 62% have achieved viral suppression vs. 25% in sub-Saharan Africa 71% of HIV patients adherent vs. 77% in sub-Saharan Africa

  4. Fickle global donor community that recognizes the role of non-communicable diseases. 87% of global funding = HIV 200,000 AIDS-related deaths (< 40%) 66% of deaths worldwide = NCDs

  5. Behavioral interventions which have failed to be Cost-effective Useful Realistic Evolve with time Sustainable.

  6. Our current scientific norms limit ability to provide CURES. PI driven models Manual-based training Not responsive to context Replication with fidelity Female models of tend/befriend Interpersonal

  7. Prevention scientists are often like architects who design custom houses, unique for each setting.

  8. Each EBI builds its own structure, process, & content .

  9. Each existing EBI is unique & special, “over-serving the needs” of families.

  10. Disruptive Innovations are simpler, cheaper, & good enough solutions.

  11. Cultural Tailoring Local Ethnicity, Language, Adaptation Income, Education Shared processes: Dom ains (anxiety, obesity); Frame issue Situations (enter new school); Apply knowledge Content Developm ental challenges Build skills Tailoring (parenting 0-5, 6-9, 10-12) Remove barriers Build social support Foundational Practice Elem ents (n=14) utilized to implement a set of Skills Com m on Principles (10) A model for conceptualizing a training model to diffuse evidence-based interventions.

  12. 4 million Community Health Workers (CHW) are poorly trained & provide inconsistent care.

  13. Philani founded in 1 9 7 9 in the Cape Tow n tow nships Accountability Visit all homes Connect with families Carry entre task Community ties & decision making Weak: Behavior change theory

  14. CHW ( Mentor Mothers) are at the core of Philani’s program .

  15. Three innovations Build our MM’s skills & quality: Selection Training Monitoring

  16. Com m unity health w orkers ( CHW ) Mobile phones are used are at the core of throughout all aspects Philani’s program . of the project . Collect research data Monitor place, time, & content of intervention delivery Provide MM & their supervisor data on content, process, & outcome.

  17. Mobile phones help CHW to provide effective support & monitoring.

  18. Mentor Mothers visit every household, clicks her phone on entry, indicates content, & gives feedback at end.

  19. Target challenge: 14% underweight; 30%, HIV+; 6.5% Fetal Alcohol Syndrome.

  20. Assessm ents at Baseline, Post- Birth, 6 , 1 8 , and 3 6 m onths • 5 com pleted: 8 0 .6 % • 4 com pleted: 9 1 .4 % • 3 com pleted: 9 5 .6 % • 2 com pleted: 9 8 .9 %

  21. Follow-up Rates (N=1238) 100 90 80 70 60 50 % 40 30 20 10 0 2-Weeks Post- 6 month 18 month 36 month birth

  22. Randomization worked well. Neighborhoods were highly similar. Shebeens Size Density Water sources Formal / informal housing Rates of HIV Migration history

  23. Mothers were highly similar across conditions. Age, Education Income Number of previous children Low Birth Weight previously HIV status Partnerships

  24. Baseline Characteristics of MLH and MWOH 35 30 25 20 % HIV + 15 HIV - 10 5 0 Alcohol AUDIT > 2

  25. Linked to Care • Perinatal 8 3 .5 % • 6 m onths 4 6 .5 % ( 6 8 % ARV) • 1 8 m onths 5 4 .5 % ( 8 7 % ARV) • 3 6 m onths 6 6 % ( 8 0 % ARV)

  26. Disturbing • HI V + Status ( control group) – Antenatal 3 2 % – 3 6 m onths + 5 % • Deaths – Maternal ( 3 5 / 1 4 0 ) 2 5 % – I nfant 8 .9 %

  27. SC PIP HIV+ Mothers: Infant Health At 18 Months 60.0% SC PIP 50.0% 40.0% 27.7% 30.0% 24.6% 17.9% 16.9% 20.0% 13.2% 8.4% 10.0% 0.0% Weight-for-age z- score ≤ -1* Height-for-age z- score ≤ -2* Treated at clinic: High fever* Significant at the 10% level, adjusted for neighborhood clustering. *Significant at the 5% level.

  28. Intervention work??

  29. Baby nutrition outcom es for the I ntervention Condition Predicted Weight for length z-score of Intervention Infants by Mother's antenatal depression status 2.00 Mean weight for length 1.50 1.00 0.50 EPDS > 18 EPDS ≤ 18 0.00 -0.50 -1.00 Post birth 6 months post birth Time

  30. Height-for-age Z-scores Over Time, Stratified by Severe Antenatal Depression (EPDS>18) 0.60 0.40 0.20 0.00 -0.20 -0.40 SC Not Depressed SC Depressed -0.60 PIP Not Depressed PIP Depressed -0.80 -1.00 -1.20 -1.40 Post Birth 6 Months 18 Months Among the SC, infants of mothers depressed antenatally have significantly lower HAZ scores at 6 months (p=<0.01); however, among the PIP, infants of mothers depressed at baseline do not have significantly different HAZ scores. Looking within mothers depressed during pregnancy, PIP infants have significantly higher HAZ at 6 months (p<0.01), and a significantly more positive change in HAZ between post-birth and 6 months (p=0.04). Note that f or n=94 late-entry participants, depression during pregnancy was not assessed. Depression at the time of the late-entry assessment is used as a proxy for antenatal depression.

  31. SC PIP Mothers Depressed Antenatally (EPDS>18): Infant Health At 18 Months 60.0% SC PIP 49.2% 50.0% 40.0% 30.5% 28.6% 30.0% 20.0% 15.7% 10.0% 0.0% Child had cough last two weeks* Since birth child admitted to hospital* Significant at the 10% level, adjusted for neighborhood clustering. *Significant at the 5% level.

  32. Feeding Habits Among Mothers Ever Severely Depressed 10 Control 8.6% 9 8 7 7 Percent / Mean / Median 6 5 4 4 3.3 2.7% 2.6 3 2 1 0 Percent breastfed exclusively first Mean months breastfed Median count of non-breast-milk 6 months* exclusively * food items *

  33. SC PIP Among All Subjects: Maternal And Infant Health At 18 Months 60.0% SC PIP 50.0% 40.0% 30.0% 24.8% 17.2% 20.0% 8.1% 10.0% 4.1% 0.0% Mother currently diagnosed with hypertension* Child had diarrhoea last two weeks* Significant at the 10% level, adjusted for neighborhood clustering. *Significant at the 5% level.

  34. SC PIP HIV+ Mothers: Condom Use At 18 Months 90.0% SC PIP 76.6% 80.0% 70.0% 62.0% 60.0% 46.6% 50.0% 40.0% 31.5% 30.0% 20.0% 10.0% 0.0% Condom use 10 out of last 10 times* Method family planning: Condom* Significant at the 10% level, adjusted for neighborhood clustering. *Significant at the 5% level.

  35. CHW hom e visitors significantly I m prove m aternal & child health.

  36. W e have been reinventing the w heel; w hat has w orked has been the sam e across EBI .

  37. W e know of five innovations w hich w e think consistently im prove im plem entation of CHW Case assignment Training model Contact strategy Phone & in-person contact Length of intervention

  38. Healthy families will require: Synthesize common elements, practices, principles Experiment with delivery formats Market strategies to diffuse Adopt continuous quality improvement

  39. MEN ????? Not In Women’s Settings With Women’s Norms

  40. Men are not going to be engaged in fem ale oriented structures. W ORK & PLAY

  41. The Philani Plus Team thanks you.

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