A revolutionary antimicrobial innovation creating solutions for the - PowerPoint PPT Presentation

NordShield - developed by nature, perfected by science A revolutionary antimicrobial innovation creating solutions for the 21 st century STRICTLY PRIVATE AND CONFIDENTIAL | NORDIC BIOTECH GROUP LTD. STRICTLY PRIVATE AND CONFIDENTIAL | NORDIC BIOTECH GROUP LTD.

Antimicrobial, identified disadvantages Guanidines • Commonly used sensitizers • carcinogenic properties (category II) • High aquatic toxicity properties Quats • Non-biodegradable and accrue in nature Parabens • Cause estrogenic and allergenic effects Triclosan • Hormonal effect • Allergic sensitization • Antimicrobial resistance Isothiozolinones • Commonly used sensitizers • High aquatic toxicity properties STRICTLY PRIVATE AND CONFIDENTIAL | NORDIC BIOTECH GROUP LTD.

The technology – How NordShield works NordShield ’s technology is based on nature’s way to fight microbes • A major component of wood is cellulose, a complex form of sugar, and a perfect energy source for harmful microbes. • Through the entire evolution period, trees have developed an optimal defense mechanism against harmful fungi, bacteria and viruses. • A major player in this mechanism is a set of chemicals called resins – that have been used for healing wounds and infections for thousands of years. • Through modern chemistry and science, nature’s mechanism has now been opened for modern consumers by re- engineering nature’s inventions. STRICTLY PRIVATE AND CONFIDENTIAL | NORDIC BIOTECH GROUP LTD.

The cellular effect – Tested application; NordShield water based mixture Studies conducted by the University of Helsinki Killed S. aureus ATCC12598 visualizing the results from ATP and SEM 100,00% 80,00% 60,00% 10 min The results showed that both 0.5 % NS 1.0 % NS 30 min 40,00% Gram-positive and Gram-negative mixture mixture 1 h can effectively be completely killed 20,00% with 0.5 % mixture in 30 min. 0,00% No compound 500 µ l compound/ml 1 ml compound/ml Killed E. coli DH5 α 100,00% 80,00% 60,00% 10 min 30 min 40,00% 1 h Microbe concentration used: > 10 000 000 cfu/ml. 0.5 % NS 1.0 % NS 20,00% mixture mixture 0,00% No compound 500 µ l compound/ml 1 ml compound/ml STRICTLY PRIVATE AND CONFIDENTIAL | NORDIC BIOTECH GROUP LTD.

The technology – molecular net formation Tampere University of Technology Tampere University of Technology The mechanism shown on non-woven fibres The mechanism shown on non-woven fibres treated with NordShield’s ethanol based treated with NordShield’s water based mixture mixture (0,08% solution) after ethanol (1,0% solution) after water evaporation evaporation STRICTLY PRIVATE AND CONFIDENTIAL | NORDIC BIOTECH GROUP LTD.

Fiber tests Determination of fungi static activity on single textiles and pile of textile products Baltiachemi OÜ Baltiachemi OÜ Test microbe: Aspergillus brasiliensis Test time: 18 days Quantity of active substances: 200ppm Standard: Modified EVS-EN ISO 20743:2013 Product: Water based NS solution Untreated sample Treated sample • after two days white hyphae is developed • after four days spores develop STRICTLY PRIVATE AND CONFIDENTIAL | NORDIC BIOTECH GROUP LTD.

NordShield product categorization Liquid Solid Water based Solvent based Liniments Polymers solutions solutions STRICTLY PRIVATE AND CONFIDENTIAL | NORDIC BIOTECH GROUP LTD.

Addressable Dressings and markets Bandages Surgical sheets Garments & Patient curtains Medical Surface devices disinfectants Medical Filter systems Dialysis disposables Geo Upholstery textiles Transportation Air Construction Insulation filtration NordShield Filtration Textiles targets extensive Liquid soaps markets with a clear Shoes Fabric and focus on applications homecare Garments Deodorants In can preservation Incontinence Water & air filtration Food Fibers packaging STRICTLY PRIVATE AND CONFIDENTIAL | NORDIC BIOTECH GROUP LTD.

Selected target markets – Filtration systems Spun lace / non-woven test results Baltiachemi OÜ Tampere University of Technology Sample a Material 70% Viscose 30% Polyester 0,5 ml /0,4 g log red. R 1,0% >8,0 (99,999999%) 0,5% >8,0 (99,999999%) 0,2% =3,1 (>99,9%) Treated fiber • Product: Water based NS solution • Standard: EN 20743, 24h • Impregnation time 3-4s • Microbe: S. Aureus STRICTLY PRIVATE AND CONFIDENTIAL | NORDIC BIOTECH GROUP LTD.

Selected target markets – Fibers Durability comparison between NordShield and leading silver based product Tampere University of Technology 0 washes Microfiber 50 washes 65% Viscose Standard: EN 20743 31% PES 4% Spandex Microbe: S. Aureus R=5,0 (99,999%) R> 4 (>99,99%) NordShield Silvadur R=3,7 (>99,9%) R> 3 (>99,9%) Washing conducted by professional Textile hospital laundry Uudenmaan 62% PES Sairaalapesula Oy 35% COT 3% Spandex R=5,2 (>99,999%) R> 3 (>99,9%) NordShield Silvadur R=5,3 (>99,999%) R> 3 (>99,9%) STRICTLY PRIVATE AND CONFIDENTIAL | NORDIC BIOTECH GROUP LTD.

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