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1 Introduction of XtremIA 5th of December 2017 10 Janvier 2016 - PowerPoint PPT Presentation

Oct 12, 2022 •19 likes •289 views

1 Introduction of XtremIA 5th of December 2017 10 Janvier 2016 Pierrick DREVILLON, Msc, MBA ESCP (Paris) Co-foundeur of Xtremia INSEMINATION 2.0 FOR ALL FARMERS , FOR ALL SPECIES A T TECHN HNICAL CAL REVOLU LUTI TION, ON,

  1. 1 Introduction of XtremIA – 5th of December 2017 10 Janvier 2016

  2. Pierrick DREVILLON, Msc, MBA ESCP (Paris) Co-foundeur of Xtremia INSEMINATION 2.0 … FOR ALL FARMERS , FOR ALL SPECIES

  3. A T TECHN HNICAL CAL REVOLU LUTI TION, ON, INSEMIN MINATION ATION 2.0. THE DEEP ARTIFICIAL INSEMINATION: AN ALREADY MASTERED TECHNIQUE!

  4. AI : an omnipresent technique in the world … 110 million ≈ 100 000 Almost 100% of AI in the 2.8% of born 80% of born for some bird mares world children in piglets species like inseminated France 1 / 2 cow in / year turkey France AI : a growing ng-up p techniq nique ue for the last t 70 70 years ! 4

  5. 5 An increasingly reduced fertility in World Dairy farms … • Lack of expression (low • Negative genetic Selection at P4 rates) correlations between • Lack of observation by the expense milk production and of fertility the breeder fertility On average: ↑ of the -50% fertility on Montbéliarde Insufficient number of cows in AI1 heat animals with -45% in Normande cows detection genital risks - ≈ 35% in Holstein cows (Le Mezec et al, 2010) • Selection of overturned • Sexed semen (2M basin animal  Use of new spz/dose) ≠ biotechnologies uro/pneumovagina conventional semen (10M spz/dose)

  6. 6 Development of Deep AI in species Genital tracts  AI in fresh  AI in fresh and frozen  AI in fresh and frozen  Dose price: 3-7 €  Dose price: 200-3 000 €  Dose price: 25-50 €  Goal: prolificacy  Goal: low [dose]  Goal: Sexed semen

  7. 7 Development of Deep AI in species Existing DAI devices 75 cm Equine deep AI catheter (Minitüb) Ghent Device (University of Gand), Aspi Gun (IMV), Extra-Flex (Minitüb) ? DeepGoldenPig (IMV), Gédis (Gènes Diffusion), UnicSoft (Cobiporc)

  8. A TECHNICAL TECHNICAL RE REVOLUTIO VOLUTION, N, IN INSEMINATIO SEMINATION N 2. 2.0. 0.

  9. 9 XtremiA : a real changing equipment … A safe handling… • Direct use of 0.25ml straws in the device : no risk of destruction of the sperm. • Drop off by a retraction of the sheath : securing the gesture for the animal. Health safeguards… The final touch... • Individual packages with sanitary • Drop the semen up to 25 cm into sheats. the uterine horn. • Consumable and non reusable • Without any constraint for the sheats. operator: the material adapts itself to the animal anatomy. • Perspective of diversification in ET.

  10. 10 Xtrem-ET : the revolution in embryo transfer Esayslide, a specific cap with a lateral exit … Time for Embryo Transfer 2.0 Reduced cross-section for a better passage through the closed cervixes of recipients of Rounded extremity with a heifers dilatory effect to facilitate the catheter’s progression into the cervixes

  11. 11 Xtrem-ET : the revolution in embryo transfer The first The end of Improved Use cows as transfer device spinal results recipients ! for all users ! anaesthetic

  12. A T A TEC ECHN HNICAL CAL REV EVOLUTI LUTION, ON, INSEMIN MINATION ATION 2.0. NON-EXHAUSTIVE APPLICATION EXAMPLES IN BREEDING

  13. 1. SEXED SEMEN

  14. Number of spermatozoids/AI Spectrum of action of the dose male spermatozoids Spectrum of action of the Spectrum of action of the In millions of female spermatozoids female sexed semen spermatozoids/AI dose 12 10 8 6 4 2 5 h 7h 9h 11 13 15 17 19 21 23 1 3 5 7 9 11 13 14 Time Minimum 12h Fertilization window IA Heat detection Sexed semen

  15. Millions Billion Thousands

  16. Millions Spermatozoids in strength and number

  17. 17 Results of the tests conducted during summer 2014 Experimental results: • Calving rates, depending on the type of semen 70.00% + 15.2% difference(+ 6.43 pts) ! b 57.7% 60.00% a a 51.3% 48.7% b 50.00% 42.3% 40.00% E N = 314 N = 662 T 30.00% 20.00% 10.00% 0.00% Sexée Gestation Sexée Pas de gestation

  18. 2. EMBRYOS

  19. The epidural: a working comfort, a guarantee for the breeder , but… 19

  20. No more epidural Simplified pose

  21. 3. HIGHLY PRODUCING COWS

  22. Ketones ↑ the prevalence of mucus ↑ the appearance of free radicals ↑ the inflammation

  23. 4. THE CASE OF THERMAL STRESS

  24. THERMAL STRESS

  25. THERMAL STRESS

  26. www.xtremia.fr Suivez-nous sur Facebook ! XtremiA remiA ALL OF US HAVE TO IMAGINE THE TOMORROW’S APPLICATIONS...

  27. www.xtremia.fr

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