Digital North Accelerator Programme Zilico Ltd present ZedScan
Introduction Yorkshire and Humber AHSN, Health Innovation Manchester, Innovation Agency North West Coast and North East and North Cumbria AHSN are working together to help innovative digital SMEs within their regions to increase their adoption across the whole of the north of England. To achieve this the Digital North Accelerator Programme has been established to deliver a range of supporting activity to facilitate adoption and spread. It will also form a funnel for the Innovation Exchange where those best suited for national adoption will be identified
AHSNs exist to encourage innovation in health and care and to stimulate growth in industry and the life sciences. Our vision is to improve the health and prosperity of our regions by unlocking the potential of new ideas. Across the country AHSNs act as a bridge between healthcare providers, commissioners, academia and industry. By connecting these sectors, we help to build a pipeline of solutions for the NHS from research and product development through to implementation and commercialisation. Locally, we work in partnership with our regional health and care community and develop projects, programmes and initiatives that reflect the diversity and meet the needs of our local populations and healthcare challenges. Together, we breathe life into innovations that improve care, effectiveness and efficiency in the NHS and social care. In the year ahead we will continue to accelerate the spread and adoption of innovations with proven impact and value so that the healthcare system in our regions gains the maximum benefits more quickly
Agenda • Company overview • Clinical challenge • Electrical Impedance Spectroscopy and ZedScan -a diagnostic tool • Value - health economics and patient outcomes – Bradley Quinn • User testimonial – Bradford Royal Infirmary experience • Real world of innovation adoption in the NHS – ELHT experience • Q and A
1 1. Adjunctive colposcopy technologies for assessing suspected cervical abnormalities: the DYSIS colposcope with DYSISmap and the ZedScan I Diagnostics guidance [DG32] Published date: April 2018 https://www.nice.org.uk/guidance/dg32
ZedScan Clinical Testimonial – Bradford Royal Infirmary experience Mr Nicholas Myerson, Clinical Lead for Obstetrics and Gynaecology Suzanne Taylor, Lead Nurse Colposcopist and Cervical Screening Programme Lead Bradford Royal Infirmary Click to watch
Bradley Quinn Insight and Intelligence Lead, Health Innovation Manchester
Real World of innovation adoption within the NHS – Burnley Hospital Ms Uma Krishnamoorthy MBBS, MRCOG, MBA Associate Medical Director (A&R), Consultant Gynaecologist and Lead for Colposcopy, East Lancashire Hospitals NHS Trust Click to watch
Q&A Training Manager – Alison Roberts RGN, MA - alison.roberts@zilico.co.uk Chief Executive – Sameer Kothari - sameer.kothari@zilico.co.uk VP Sales – Darren Neill – Darren.neill@zilico.co.uk
Appendix of published data - This is not an exhaustive list ZedScan-related publications 1.B H Brown, J Tidy, K Boston, A D Blackett, R H Smallwood and F Sharp, (2000), The relationship between tissue structure and imposed electrical current flow in cervical neoplasia, The Lancet, 355: 892-95. 2.Abdul S, Brown BH, Milnes P and Tidy J, (2006) The use of Electrical Impedance Spectroscopy in the detection of Cervical Intraepithelial Neoplasia, Int. J Gynaecological Cancer, 16, 1823-1832. 3.Abdul S, Brown BH, Milnes P and Tidy JA, (2005) A clinical study of the use of impedance spectroscopy in the detection of Cervical Intraepithelial Neoplasia (CIN), Gynecol. Oncol. 99,3, S64-S66 4.Brown BH, Milnes P, Abdul S and Tidy JA. (2005) Detection of cervical intraepithelial neoplasia using impedance spectroscopy: a prospective study, Br J Obstet Gynae: 112, 802-806. 5.Balasubramani L, Brown BH, Healey J, Tidy JA. (2009) The detection of cervical intraepithelial neoplasia by electrical impedance spectroscopy: The effects of acetic acid and tissue homogeneity Gynecol Oncol 115(2):267-71. 6.JA Tidy, BH Brown, TJ Healey, S Daayana, M Martin, W Prendiville, HC Kitchener. (2013) Accuracy of detection of high-grade cervical intraepithelial neoplasia using electrical impedance spectroscopy with colposcopy Br J Obstet Gynae 120; 400-411 7.Brown, B., Tidy, J., Healey, J., Highfield, P.,(2013) Supplementary Information relating to EIS performance: Personal Communication 8.National Institute for Health and Care Excellence, Medical Innovation Briefing. 2015, "The ZedScan as an adjunct to colposcopy in women with suspected cervical intra-epithelial neoplasia". 12th February, 2015 9.MacDonald, M.C., Lyon, R., Palmer, J.E., Tidy, J.A. (2015), "The routine use of ZedScan within one colposcopy service in England", unpublished presentation at the BSCCP Annual Meeting, 15-17th April, 2015, Nottingham, UK. 10. C. MuszynskiE. DupontB. VaysseS. LantaJ. TidyF. SergentJ. Gondry (2017), The impact of using electrical impedance spectroscopy (ZedScan) on the performance of colposcopy in diagnosing high grade squamous lesions of the cervix http://dx.doi.org/10.1016/j.jogoh.2017.08.007 11.MacDonald M.C. et al. (2017), Influence of high risk HPV genotype on colposcopic performance: A large prospective study demonstrates improved detection of disease with ZedScan 1, particularly in non-HPV 16 patients. European Journal of Obstetrics & Gynecology and Reproductive Biology 211 pp.194 – 198 12. Macdonald M, Crossley J, Ellis K, et al. (2018) Prevalence of high-grade cervical intraepithelial neoplasia in women with persistent high-risk HPV genotypes and negative cytology. Cytopathology; 00:1 – 10. https://doi.org/10.1111/cyt.12516 13. J. Tidy , B. Brown, J Healey, J. Palmer(2018) Increased detection of high grade glandular intraepithelial neoplasia (HG-CGIN) by electrical impedance spectroscopy (ZedScan); presented at BSCCP
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