Translational Research ― From Laboratory to Marketplace: University of Houston‚s Strategy RATHINDRA N. BOSE Vice Chancellor for Research and Technology Transfer 1 University of Houston System
Division of Research Functions Strategic Economic Securing and investment & development managing Fostering through external grants multidisciplinary translational and contracts research research Structures Pre-Award Technology � � Commercialization Post-Award � Centers and Compliance � � Institutes Animal Care �
Productivity at a Glance FY 2011 1,386 proposal submitted 47 invention disclosed 29 provisional patents filed 478 awards managed 25 utility patents filed 482 IRB protocol reviewed 141 active U.S. patents issued 49 IACUC protocol reviewed 42 active licenses 15 active startups 16 revenue sources Inventors (over $100,000) Harold Kohn, Diana Chow, Alexandre Freundlich, Paul Chu, Venkat Selvamanickam
Ever-expanding Faculty Roles HEART OF ACADEMIC INSTITUTIONS CREATOR OF: � New knowledge � New technology Tomorrow’s Scholars � � New world THE CAPITAL OF KNOWLEDGE-BASED ECONOMY
The University: An Economic Engine! Prepare highly skilled and • educated citizens Security Create new knowledge • (understanding, ideas, innovation) Prosperity Jobs Create jobs • - Technologies Health - Processes Sustainability - Products Contribute to economic growth and • global competitiveness Benefits to the nation and world Institutions are knowledge capitals Source: Part from ASTRA
Major Functions: Technology Transfer and Economic Development Manage License Patent Intellectual Portfolio Property Liaison with regional economic Start-up planning and companies development organization
Stages of Technology Transfer Demonstr- Market Growth & Imagining Incubating ating Entry Sustainability Products & the to Define to Generate to Prove Processes in Commercial Commercial Financial Commercial Commercial Opportunity Potential Returns Viability Context � � � � Mobilizing Mobilizing Mobilizing Mobilizing Resources for Resources for Resources for Resources for Demonstrating Market Entry Growth & Incubating Sustainability Source: The Ohio Third Frontier Program
Letter signed by 135 Presidents/Chancellors, including Chancellor Khator.
Re-engineer Tech Transfer Operations Invest to create prototypes • (valley of death!) Expedite transfer of laboratory research to market place • (support faculty entrepreneurs, develop partnership with industries, create advisory board, explore IP assignment to research park) Pursue aggressive licensing agenda • (adopt sound marketing strategies) Expand IP portfolios • (hold regular workshops, seminars by successful faculty role models, rewards) Attract venture capitals for new spin-off companies • (Organize tech shows, invite venture capitalists, publicize success stories etc.) Enhance public-private partnership in pursuing marketable research • projects
Balancing the Need for an Open Science Regime vs. the Desire for Confidentiality and Exclusivity IP agreements Memoranda of � ownership understanding � patenting � parties � licensing rights � scope of work � confidentiality/ � responsibilities publishing � timelines rights � deliverables
Conflicting Views: Differences in Motives, Processes and Working Practices Industry Reasons for Participating in Partnerships: Access to new research � Development of new products � Maintaining a relationship with the university � Obtaining new patents � Solving technical problems � Viewed as less important: Improving products and recruiting students � University Reasons: Obtaining funding for research assistants, lab equipment and research � Obtaining insights into their research by field testing theory and empirical � research Viewed as less important: Acquiring practical knowledge useful for teaching, � student internships and job placement, and obtaining patentable inventions and business opportunities . Source: Lee, Y.S. (2000) The Sustainability of University-Industry Research Collaboration. J. Tech. Transfer, 25(2), 111-133.
Technology Commercialization Ecosystem Technology Foundation & Incubator Valuation & Proceeds IP Market Analysis Proceeds Assignment Market Entry Technology-Specific Company Formation Teams License Out Development Work Faculty’s Lab
Expected Benefits • Increased Research Expenditure • Increased Royalty Revenue • Increased Postdoctoral Appointments • Increased Translational Research • Recruitment of Entrepreneurial Faculty • Creation of Jobs
Ten Measures for Top 50 U.S. Universities 1. Total Research Expenditures 2. Federal Research Expenditures 3. National Academy Membership 4. Faculty Awards 5. Doctorates Awarded 6. Postdoctoral Appointees 7. National Merit and Achievement Scholars 8. Endowment Assets 9. Annual Giving 10.SAT Scores Source: The Center: The Top American Research Universities
Thank you.
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