prevalenza anni 80 anni 80 comunit europea 2000
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PREVALENZA : ANNI 80 ANNI 80 Comunit Europea 2000 6403 sera - PowerPoint PPT Presentation

PREVALENZA : ANNI 80 ANNI 80 Comunit Europea 2000 6403 sera Tissue transglutaminase testing 134 tTg+ ( > 7) 3 tTg - (5.1-6.9), EMA + PREVALENZA 1: 49 8 CD without 6 CD diagnosed 120 antibody + GFD diagnosed between 2000 33tTg >


  1. PREVALENZA : ANNI 80

  2. ANNI ‘80

  3. Comunità Europea 2000 6403 sera Tissue transglutaminase testing 134 tTg+ ( > 7) 3 tTg - (5.1-6.9), EMA + PREVALENZA 1: 49 8 CD without 6 CD diagnosed 120 antibody + GFD diagnosed between 2000 33tTg > 7, EMA – before 2000 and 2002 87 tTG > 7, EMA 123 individuals to be biopsied 81 (66%) 17 (14%) 21 (17%) 4 (3%) had died aggred on refused could be not after serum biopsy be traced sampling 40 biopsied so far

  4. Prevalence of coeliac disease among 5055 pregnant women TUTTA LA CAMPANIA 2000 TGASE Units n EMA EMA DQ DQ DQ2/ DQ2/ DIAGNOSI RATE + - 2 8 8 8- S TGASE > 9 48 48 42 4 1 1 48 Coeliac UI >7 TGASE< 9 10 3 7 4 1 - 5 6 Coeliacs UI >5 TGASE<7 20 0 20 6 1 13 2 Coeliacs UI TGASE < 5 4977 Negative TOTAL 5055 51 27 50 6 2 20 56 New cases Known cases 12 Known 12 1:74 1:4,6

  5. Celiaci tra bimbi immigrati in Italia Italian areas Immigrant CD patients Total CD patients % ( n = 34 ) ( n = 1764 ) NORTHERN 11 615 1.8 CENTER 15 603 2.5 8 546 1.5 SOUTHERN – INSULAR* ____________________________________________________________________ * Insular = Sicily

  6. TABLE 1: Geographic distribution in our country of the immigrant CD patients _______________________________________________________ EAST EUROPE : Macedonia ( 1 ), Rumania ( 3 ), Poland ( 2 ), Russia ( 2 ), Serbia ( 1 ), Albania ( 5 ) NORTH AFRICA : Egypt ( 1 ), Morocco ( 6 ), Tunisia ( 4 ), Saharawi ( 2 ) WEST AFRICA : Cape Verde ( 1 ) EAST AFRICA : Somalia ( 1 ) MIDDLE- EAST : Syria ( 1 ) SOUTHERN : Sri-Lanka ( 1 ), Pakistan ( 3 ) ASIA ______________________________________________________

  7. QUEST’ANNO 2006 1:33 1:41 1:50 1:60 Tunisia 1: 45

  8. In the recent past One in every 50-100 common people, many apparently healthy

  9. epilessia atassia Lesioni smalto dentario iridociclite esofagite tiroidite cardiomiopatia gastrite pancreatite epatite diabete colite diarrea ulcere nefrite amenorrea Dermatite Erpetiforme distrofia neurite artrite anemia

  10. � Sintomi • Epilessia e calcificazioni � Sintomi atipici cerebrali � Patologie associate • Sclerosi Multipla � Complicanze • Emicrania • Alopecia • Riduzione diametro capelli capelli • Atassia glutine • Uveite dipendente • Cataratta Cataratta • Lesioni smalto dentario • Ipoacusia • Stomatite aftosa • Modifiche salivare • Tiroidite • GERD • GERD • Carcinoma papillare della • Esofagite eosinofila tiroide • Sindrome di Plummer-Vinson • Iperparatiroidismo (Paterson-Kelly) (Paterson-Kelly)

  11. � Sintomi • Depressione � Sintomi atipici • Ansietà � Patologie associate • Disturbi della � Complicanze sfera affettiva • Sjögren • Osteoporosi • Sarcoidosi • Fratture • Emosiderosi • Cardiomiopatia • Debolezza • Fibrillazione muscolare • Iper-CK-emia atriale • Vomito • Epatite • Gastrite • Cirrosi biliare linfocitaria primitiva • Diabete • Colangite sclerosante • Insufficienza • Ipertransaminasemia Pancreatica

  12. � Sintomi • Anemia ferrocarenziale � Sintomi atipici • Anemia megaloblastica � Patologie associate • Porpora trombocitopenica � Complicanze • Trombocitosi • Diarrea • Iposplenismo • Iposplenismo • Dolori addominali • Nefrite • IBS • Insufficienza renale cronica • Colite • Tumori Intestinali • Cavitazione • Amenorrea • Infertilità linfonodi mesenter • Aborti ricorrenti • Dermatite Erpetiforme • Neuropatie mot • Psoriasi • Gangliopatie • Keratosis Pilaris sensoriali • Xerosi cutanea • RLS (Restless Leg Syndrome ) • Artrite • Artrite • Artrite reumatoide

  13. www.medicel.unina.it

  14. But know how and diagnostic facilities VERY different Most patients cared for Few patients appropriately cared for well Care very occasional, start after 6 years ! What about the infants ?

  15. Que c’es qu il a en Algerie ?

  16. Le celiaquie en Algerie en 2020 Population 33.769.669 Trouble digestif 51.040 Enfant 0-14 an 8.878.665 Anemia 24.019 CELIAQUE 337.697 Osteoporosis 18.014 ENFANTS 88.787 Anomalies du foie 6.005 Celiaque Arête de Croissance 4.000 COUT DE LA € 123.410.460 Dinar CELIAQUE 123.420.500.000 Excess de mort 14.118

  17. Consumption of wheat per capita (Kcal/Day)

  18. Rise in the consumption of wheat flour

  19. Pasta consumption in the E.U. (1990 - 2008)

  20. CONSUMPTION OF Production of pasta in PASTA PER CAPITA the world ������������� ��������������� ������������������ ������ ������ ������ ���������� ������������� "���� ���������� ������ ������ ����������������� ����� ������ ����� ���������� ������������� ������ ���������� �!�� ������ ������������������ �������������� "���� ������

  21. ��"���##���������$%#&��%#��'������������� ����� %���%%"���"(��"�"������� ������ ����� ����� ���������� �������� ������ ������� ������� ����������� ������ ����� ����� ���� ������� ������� ��� �� ��!���� ������ ������ �!��� ����� ����� �������

  22. )�����������*�������� ��������� ��������� ����������������� ����������������� ��������������������� ������� ����� ������ ��������������������� �������������������� �������������������� ����� �� !"��#� !$"��%% !$���&" �� !�''' ������ �'���&' !%� &� !%��" �'%�$$% (����� &'"�&"� !�'� $ !!��!!' #!&��%$ ���� %%���%& %!� &' ��%�% " %#��%!# )�*�� �� ���'�" ' ��!'$ $!&���$ ��&"����$ (������ '�$$ � &# #"#�%�" ���'��!!� '�##$�'"

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