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PAOLA-1 STUDY Platine, Avastin and OLAparib in 1 st line of advanced - PowerPoint PPT Presentation

PAOLA-1 STUDY Platine, Avastin and OLAparib in 1 st line of advanced high grade epithelial ovarian, fallopian tube, or primary peritoneal cancer. Randomized, Double-Blind, Phase III Trial of Olaparib vs. Placebo in Patients with Advanced FIGO


  1. PAOLA-1 STUDY Platine, Avastin and OLAparib in 1 st line of advanced high grade epithelial ovarian, fallopian tube, or primary peritoneal cancer. Randomized, Double-Blind, Phase III Trial of Olaparib vs. Placebo in Patients with Advanced FIGO Stage IIIB – IV High Grade Serous or Endometrioid Ovarian, Fallopian Tube, or Peritoneal Cancer treated with standard First-Line Treatment, Combining Platinum-Taxane Chemotherapy and Bevacizumab Concurrent with Chemotherapy and in Maintenance . Principal Investigator : Pr Isabelle Ray-Coquard, MD Centre Léon BERARD, Lyon, France

  2. PAOLA -1 Study design

  3. Recruitment status_13/05/2016 454 registered patients including : - 166 randomized patients - 103 screened failure

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