on the future of probiotics research
play

On the future of probiotics research Dr. Olaf Larsen Probiota 2020, - PowerPoint PPT Presentation

Mar 17, 2023 β€’487 likes β€’683 views

On the future of probiotics research Dr. Olaf Larsen Probiota 2020, Dublin Conflicts of interest Associate Professor @ Athena Institute, Vrije Universiteit Amsterdam (0.2 FTE) Senior Manager Science @ Yakult Nederland B.V. 2 Short

  1. On the future of probiotics research Dr. Olaf Larsen Probiota 2020, Dublin

  2. Conflicts of interest β€’ Associate Professor @ Athena Institute, Vrije Universiteit Amsterdam (0.2 FTE) β€’ Senior Manager Science @ Yakult Nederland B.V. 2

  3. Short company profile 3

  4. On the future of probiotics research 4

  5. Responders & non-responders Kootte, Ruud S., et al. Cell metabolism 26.4 (2017): 611-619. 5

  6. The challenges 1. A fair meta-analysis 2. A personalized approach Kootte, Ruud S., et al. Cell metabolism 26.4 (2017): 611-619. 6

  7. 1. The (partly) fair meta-analysis: strain-specificity Hill, Colin, et al. Nat Rev Gastroenterol Hepatol 11.8 (2014): 506-514. 7

  8. 1. The (truly) fair meta-analysis: product-specificity Flach, Koks, v.d. Waal, v.d. Nieuwboer, Claassen & Larsen, Critical reviews in food science and nutrition (2017): 1-15 8

  9. 2. The personalized approach (vs the black box approach) 9

  10. 2. Microbial guilds & graph theory External trigger Physiological response 10

  11. 2. Microbial guilds: graph theory 𝐸 = 𝐹 𝑛 11

  12. 2. Directed guilds of 5 species: heatmap βœ“ 1.048.576 configurations already! βœ“ 2.490.368 paths going from node 1 β†’ node 5 Upon # nodes Larsen, et al. Scientific reports 9.1 (2019): 5558. 12

  13. 2. Weighted average density & efficiency βœ“ Directed: more efficient βœ“ Directed: more robust β€’ Larsen & Claassen. Scientific reports 8.1 (2018): 1-5. Konopka, The ISME Journal (2009) 3, 1223 – 1230 β€’ Larsen, et al. Scientific reports 9.1 (2019): 5558. 13

  14. 2. Ecological dimensions fecal transplant analogues Larsen, et al. Scientific reports 9.1 (2019): 5558. 14

  15. The future of probiotics? 15

  16. Probiotics in Europe: the future seems bright! Van der Geest, A. M., Flach, J., Claassen, E., Sijlmans, A. W., van de Burgwal, L. H. M., & Larsen, O. F. A. (2020) PharmaNutrition, 100178. 16

  17. Acknowledgements: β€’ β€’ Eric Claassen, VU Anouk Sijlmans, VU β€’ β€’ Robert Jan Brummer, Γ–rebro Universitet Mark vd Waal, VU β€’ β€’ Joop van Orsouw, Van Orsouw Design Peter vd Spek, Erasmus MC β€’ β€’ Joost Flach, VU Anton Koning, Erasmus MC β€’ β€’ Anne van der Geest, VU Yakult Questions? 17

  18. On the future of probiotics research Dr. Olaf Larsen Probiota 2020, Dublin

Recommend

Experiences of Centers Routinely Using Probiotics Probiotics and the Prevention of NEC,

Experiences of Centers Routinely Using Probiotics Probiotics and the Prevention of NEC,

Experiences of Centers Routinely Using Probiotics Probiotics and the Prevention of NEC, Death, and Sepsis S ave the dates! Monday, May 6 at 12pmET Practical Considerations and Consent - UC Davis - Emory University - Patient-family

702 views β€’ 47 slides
What they do? Regulate and increase hormone levels Manufacture B group vitamins , biotin

What they do? Regulate and increase hormone levels Manufacture B group vitamins , biotin

Probiotics: Probiotics are microorganisms, which confers health benefits to host. Probiotics restore bacterial balance and assist in digestion and assimilation. They are classified into spores, vegetative lyophilized cultures &

457 views β€’ 8 slides
Objectives Learn the history of probiotics and the importance of their unique functions in a

Objectives Learn the history of probiotics and the importance of their unique functions in a

Probiotics : Understanding the Microbiome and the Role of Probiotics in Long-term Health Jaime Capizzi, RD, LD, CLC capizzij@hotmail.com (314)616-2047 Objectives Learn the history of probiotics and the importance of their unique

1.28k views β€’ 72 slides
Leather Powered by Probiotics August 2015 Proviera Biotech is an SCD Probiotics affiliate

Leather Powered by Probiotics August 2015 Proviera Biotech is an SCD Probiotics affiliate

Proviera Biotech, LLC Kansas City, MO, USA Leather Powered by Probiotics August 2015 Proviera Biotech is an SCD Probiotics affiliate specializing in the global tannery market with sustainable environmental solutions. 1 Content Background 3

870 views β€’ 18 slides
Probiotics and the Prevention of Necrotizing Enterocolitis , Death , and Sepsis S ave the

Probiotics and the Prevention of Necrotizing Enterocolitis , Death , and Sepsis S ave the

Probiotics and the Prevention of Necrotizing Enterocolitis , Death , and Sepsis S ave the dates Monday, March 11 at 12pmET Experiences of Centers Routinely Using Probiotics - University of Utah - Kaiser Permanente, Northern California

1k views β€’ 72 slides
Probiotics : What we Know and Where we are Going Next Neerja Hajela, Ph.D. General Manager -

Probiotics : What we Know and Where we are Going Next Neerja Hajela, Ph.D. General Manager -

Probiotics : What we Know and Where we are Going Next Neerja Hajela, Ph.D. General Manager - Science and Regulatory Affairs Yakult Danone India Pvt. Ltd. Functional Food Market Probiotics an important category Global functional foods

660 views β€’ 54 slides
ADM to Acquire Neovia and Probiotics International Limited July 2, 2018 2 Safe Harbor Statement

ADM to Acquire Neovia and Probiotics International Limited July 2, 2018 2 Safe Harbor Statement

ADM to Acquire Neovia and Probiotics International Limited July 2, 2018 2 Safe Harbor Statement Some of our comments constitute forward-looking statements that reflect managements current views and estimates of future economic

439 views β€’ 14 slides
FOASC Presentation 6.8.16 1 Probiotics are surging in popularity 2 Kombucha will be $1.8

FOASC Presentation 6.8.16 1 Probiotics are surging in popularity 2 Kombucha will be $1.8

FOASC Presentation 6.8.16 1 Probiotics are surging in popularity 2 Kombucha will be $1.8 Billion in annual sales in 2020 $1.8 Billion $600 Million 3 Data Source: SPINS scan (powered by Nielsen Scantrack) L12 Weeks Ending 1/24/16 Probiotic

330 views β€’ 12 slides
Strategies for valorisation of wastes from bioethanol production lactic acid and probiotics

Strategies for valorisation of wastes from bioethanol production lactic acid and probiotics

CYPRUS 2016 4th International Conference on Sustainable Solid Waste Management Strategies for valorisation of wastes from bioethanol production lactic acid and probiotics as added value products A. Djuki-Vukovi 1 * , D. Mladenovi 1 ,

593 views β€’ 11 slides
Probiotics + Vaginas Created with Haiku Deck, presentation software that's simple, beautiful and

Probiotics + Vaginas Created with Haiku Deck, presentation software that's simple, beautiful and

Probiotics + Vaginas Created with Haiku Deck, presentation software that's simple, beautiful and fun. By Camille Freeman Photo by Koshyk page 1 of 22 Probiotics + Vaginas Created with Haiku Deck, presentation software that's simple, beautiful

435 views β€’ 22 slides
Potentials of Microorganisms for Potentials of Microorganisms for Functional Food Production and

Potentials of Microorganisms for Potentials of Microorganisms for Functional Food Production and

Potentials of Microorganisms for Potentials of Microorganisms for Functional Food Production and Probiotics Probiotics Functional Food Production and Jun Ogawa Jun Ogawa Research Division of Microbial Sciences, Research Division of Microbial

404 views β€’ 21 slides
Application of Probiotics to Control Foodborne Pathogens from Farm to Fork Mindy Brashears,

Application of Probiotics to Control Foodborne Pathogens from Farm to Fork Mindy Brashears,

Application of Probiotics to Control Foodborne Pathogens from Farm to Fork Mindy Brashears, Ph.D. Director, International Center for Food Industry Excellence Professor, Department of Animal and Food S ciences Lactic Acid Bacteria

706 views β€’ 39 slides
A Double Mask Randomized Placebo- Controlled Trial of Probiotics to Lower Microbial Translocation

A Double Mask Randomized Placebo- Controlled Trial of Probiotics to Lower Microbial Translocation

A Double Mask Randomized Placebo- Controlled Trial of Probiotics to Lower Microbial Translocation and Immune Activation in HIV-Infected Youth A multi-center clinical trial sponsored by the Adolescent Trials Network (NICHD) Protocol Chairs- John

318 views β€’ 7 slides
Fonterra Probiotics: From guts to glory James Dekker April 16, 2015 Host Institution

Fonterra Probiotics: From guts to glory James Dekker April 16, 2015 Host Institution

Fonterra Probiotics: From guts to glory James Dekker April 16, 2015 Host Institution Probiotic bacteria Live micro-organisms which, when administered in adequate amounts, confer a health benefit on the host FAO/WHO Report (2001) 3

322 views β€’ 31 slides
5 Gut Reset Recommend Foods #1 Sauerkraut #2 Kefir #3 Goodbelly Probiotics #4 Red Beet

5 Gut Reset Recommend Foods #1 Sauerkraut #2 Kefir #3 Goodbelly Probiotics #4 Red Beet

5 Gut Reset Recommend Foods #1 Sauerkraut #2 Kefir #3 Goodbelly Probiotics #4 Red Beet and Cabbage Sauerkraut #5 Bulgarian Yogurt Thank you for signing up for the 5 Day Gut Reset!

431 views β€’ 7 slides
The I talian approach to probiotics Bruno Scarpa Head of the office of special foods, food

The I talian approach to probiotics Bruno Scarpa Head of the office of special foods, food

Prom oting com petitiveness for European SMEs Enabling I nnovation in Food/ Food supplem ents The I talian approach to probiotics Bruno Scarpa Head of the office of special foods, food supplem ents and novel foods Ministry of Health, I taly

681 views β€’ 20 slides
RESEARCH ACHIEVEMENTS FUTURE RESEARCH PRIORITIES HPR 2656 HPR 2880 Director of Research CSK

RESEARCH ACHIEVEMENTS FUTURE RESEARCH PRIORITIES HPR 2656 HPR 2880 Director of Research CSK

RESEARCH ACHIEVEMENTS FUTURE RESEARCH PRIORITIES HPR 2656 HPR 2880 Director of Research CSK HP Krishi Vishvavidyalaya Palampur 176062 (H.P.) Monthly rainfall during Kh Kharif 2016 as compared to Kh Kharif 2015 in Himachal Pradesh Month

709 views β€’ 52 slides
FROM RESEARCH-LED TEACHING TO RESEARCH-LED LEARNING: EDUCATION FOR AN UNKNOWN FUTURE Emeritus

FROM RESEARCH-LED TEACHING TO RESEARCH-LED LEARNING: EDUCATION FOR AN UNKNOWN FUTURE Emeritus

FROM RESEARCH-LED TEACHING TO RESEARCH-LED LEARNING: EDUCATION FOR AN UNKNOWN FUTURE Emeritus Professor Angela Brew, Macquarie University Chair of ACUR Rising voices: young people fight for climate action Are you preparing students for this

345 views β€’ 7 slides
Health Services Research Workforce and Maximizing Its Future Thank You To Our Sponsors 2

Health Services Research Workforce and Maximizing Its Future Thank You To Our Sponsors 2

1 Understanding the Current Health Services Research Workforce and Maximizing Its Future Thank You To Our Sponsors 2 Agency for Healthcare Research and Quality Patient-Centered Outcomes Research Institute Robert Wood Johnson

350 views β€’ 10 slides
The Future of Research in Computer Games and Virtual Worlds Walt Scacchi Institute for Software

The Future of Research in Computer Games and Virtual Worlds Walt Scacchi Institute for Software

The Future of Research in Computer Games and Virtual Worlds Walt Scacchi Institute for Software Research Presented at 2012 ISR Research Forum 18 May 2012 Overview Background Future CGVW research and challenge topics Recent CGVW

630 views β€’ 17 slides
Scheduling and routing problems at TNT Some solutions and some future research directions orensen

Scheduling and routing problems at TNT Some solutions and some future research directions orensen

Vehicle routing at TNT Algorithm Future research Scheduling and routing problems at TNT Some solutions and some future research directions orensen 1 J. Vandenbergh 1 D. Cattrysse 1 M. Sevaux 2 K. S 1 Centre for Industrial Management, KULeuven

187 views β€’ 16 slides
6G Future: A Research Challenge 2nd Visions for Future Communications Summit 27.11.2019, Lisbon,

6G Future: A Research Challenge 2nd Visions for Future Communications Summit 27.11.2019, Lisbon,

6G Future: A Research Challenge 2nd Visions for Future Communications Summit 27.11.2019, Lisbon, Portugal Prof. Ari Pouttu, University of Oulu WORLDS FIRST 6G WHITE PAPER http://urn.fi/urn:isbn:9789526223544 Worlds first 6G White

272 views β€’ 14 slides
The Past and the Future in European Parliamentary Debates #dhh19 Structure 1. Research Plan

The Past and the Future in European Parliamentary Debates #dhh19 Structure 1. Research Plan

The Past and the Future in European Parliamentary Debates #dhh19 Structure 1. Research Plan & Questions 2. Results 3. Challenges 4. Outlook Research question - original How does the European Parliament talk about the future

983 views β€’ 38 slides
Bipolar Research Studies: Impact and Future State Simon Evans, PhD, Research Assistant Professor

Bipolar Research Studies: Impact and Future State Simon Evans, PhD, Research Assistant Professor

Bipolar Research Studies: Impact and Future State Simon Evans, PhD, Research Assistant Professor Gloria Harrington, LMSW, CCRP, Research Manager University of Michigan Heinz C. Prechter Bipolar Research Fund Disclosures Simon Evans

568 views β€’ 27 slides

More recommend