Medicine and Engineering at Duke
Motivation: SOM and Pratt Common Goals Diagnostics & > Clinical ENHANCING EDUCATION Therapy Medicine ADVANCING Entrepreneurship > Basic HEALTH TRANSLATION & DISEASE Science & Policy IMPROVING Enabling > HEALTH Engineering Research
The Duke Advantage: Key Assets • Top 10 medical school and top-tier hospitals • Top 10 BME program + fastest-rising engineering school (Top 20 UG, Top 30 grad) • $20M Duke-Coulter Translational Partnership • Strong clinical, research & IT infrastructure • Interdisciplinary hubs: DGHI, iiD, DTRI, I&E, DIBS • Physical proximity & culture of collaboration
MEDx Reflections
Leadership Associate Director – Ken Gall PhD (MEMS Chair) SOM Pratt • • Hashim Al-Hashimi Tosh Chilkoti (BME) (Biochemistry) • Chris Dwyer (ECE) • Ben Alman (Orthopedics) • Claudia Gunsch (CEE) • Patrick Codd (Neurosurgery) • George Truskey (BME) • Allan Kirk (Surgery) • Jennifer West (BME/MEMS) • Mary Klotman (Medicine) • Pei Zhong (MEMS) • Steve Lisberger (Neurobiology)
Initial Strategic Themes 1. Innovative and affordable and effective diagnostics and devices 2. Data science, signal processing and predictive modeling 3. Robotics-enabled basic science and clinical procedures 4. Tissue engineering and regeneration 5. Brain science and neuro-engineering
Social Engineering Weekly MEDx Café • Weds AMs at Twinnie’s and Nosh • Drop-in opportunities for students and faculty MEDx Lunch • Student-Student or Student-Faculty lunches to discuss collaborative research opportunities
New Interschool Colloquia First Inter-school Colloquia • “Duke Surgical Robotics” – Patrick Codd (Neurosurgery) and Kris Hauser (ECE) • “Challenges Seeking Solutions in Primary Care, Cancer and Engineering” – Sharon Hull (Community and Family Medicine) and Nimmi Ramanujam (BME) • “Bringing Neuro- engineering to the Clinic” – Nandan Lad (Neurology) and Craig Henriquez (BME) • “Fluid Dynamics in Virtual 3D Models of Cardiac Defects in Children” – Piers Barker (Pediatrics) and Amanda Randles (BME) • “ Microbiome Synthesis” – John Rawls (MGM), Lawrence David (MGM) and Claudia Gunsch (CEE) • “Mobile and Wireless Technologies” – Ryan Shaw (School of Nursing) and Tuan Vo-Dinh (BME)
Seed Funding Research Pilot Program RFAs ($50,000 awards) 1. VPR - Collaborative Quantitative Approaches to Problems in the Basic and Clinical Sciences (8 applications funded) • targeted to enhance interactions between faculty in the Campus departments and groups within the School of Medicine (SoM), with applications at the intersection of quantitative science and medicine 2. MEDx Interschool Collaborative Pilot Program (30 Applications Received) • targeted to enhance collaborations between the School of Medicine and Pratt faculty in the area of diagnostics and devices . • Syndicate with MEDx Leading: Surgery, Medicine, Orthopedics, Neurosurgery, DIHI, CTSA, MEMS
Diagnostics and Devices • Rapid, non-invasive, point-of-care cancer diagnostic tool Brant Inman (Surgery) and Jeff Glass (ECE) • Devices for improved tendon to bone healing Shalini Ramasunder, MD (Ortho) and Jennifer West (BME/MEMS) • A novel catheter for treatment of hydrocephaly Nandan Lad (NeuroSurg) and Ken Gall (MEMS) • A micro-physiologic system to test the tumorigenic behaviors and drug responses of skeletal muscle tumors Corinne Linardic (Peds) and Nenad Bursac (BME) • High intensity forced ultrasound and immunotherapeutic intervention for destruction of tumor cells Kim Lyerly (Surgery) and Pei Zhong (MEMS) • A miniaturized apheresis device for research and pediatric use Gow Arepally (Medicine), Neal Simmons and Hadley Cocks (MEMS)
Data Science: MEDx-iiD-Accenture 4 Teams (expanding to 8 teams 2017) • Dunson – models of intraoperative blood pressure as predictors of post- op renal function • Hauser – intraoperative patient trajectories for optimizing therapy and reducing adverse events • Heller – machine learning to manage surgical outcomes • Rai – use of EHR data for scalable framework for diabetes management
Discovery Research
Discovery Translational Research Research
Discovery Translational Commercialization Research Research
Strategic Priorities • Integration at the student level – Undergrad, post doc programs • Integration of faculty – Interschool colloquia – Seed funding • Shadowing – “Engineers in scrubs” – “ InnovateMD ” • Joint hires RFP
Strategic Priorities • Coulter enhancements • Engaging the basic science community • Collision space – Fitzpatrick CIEMAS, Downtown – Telecom – Innovation Co-Lab – DUSON – Simulation Lab • Gateway to campus talent • Thematic center grants
Thank You • Dean Andrews, Deans Katsouleas, Truskey and Bellamkonda • Provost Kornbluth • Donors – Dr. Mike Ramsey – Pamela Rosenau – The Julius H. Caplan Charity Foundation
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