Jornadas Informativa Convocatoria 2019 Reto Social 1 de H2020 - PowerPoint PPT Presentation

Jornadas Informativa ‘Convocatoria 2019 Reto Social 1 de H2020’ Oportunidades en “ Better health an care,economic growth and sustainable Health Systems ” Madrid, 17.01.2019 Juan E. Riese PhD MBA Punto Nacional de Contacto – Reto Social 1 H2020 & IMI2 Experto Nacional en el Comité de Programa Reto Social 1 Oficina de Proyectos Europeos Subdirección General de Programas Internacionales de Investigación y Relaciones Institucionales

Hablaremos de Oportunidades convocatoria 2019 en topics BHC 1. Oportunidades en el Reto Social 1: convocatorias 2019 y 2020 2. Otras oportunidades en Salud: 1. La Iniciativa de Medicamentos Innovadores IMI 2 2. European Innovation Council -EIC

Oportunidades convocatoria 2019 en topics BHC 1. Oportunidades en el Reto Social 1: convocatorias 2019 y 2020 2. Otras oportunidades en Salud: 1. La Iniciativa de Medicamentos Innovadores IMI 2 2. European Innovation Council -EIC

Pilar 3 - Retos Sociales Oportunidades convocatoria 2019 en topics BHC * *: Cifras en Millones de Euros

Reto Social 1 “Salud, Cambio Demográfico y Bienestar” Oportunidades convocatoria 2019 en topics BHC Better Health for all Envejecimiento de la población – Ciudadanos mejor informados y mayores – exigencias a los proveedores de atención médica por parte de los pacientes Solicitud de sistemas sanitarios más – personalizados y sostenibles Retos específicos: Entender mejor la salud y la enfermedad - la medicina personalizada La carga de las enfermedades crónicas e infecciosas Mejoras en el desarrollo de fármacos

Premisas conv. SC1 2019 Oportunidades convocatoria 2019 en topics BHC  Las ‘ 3 Os ’ : Open science, open innovation and open to the world  To deliver solutions for a better health for all by: – Moving towards the effective integration of personalised medicine approaches into healthcare services and systems to the benefit of patients and citizens; – Fighting infectious diseases and the growing threat of antimicrobial resistance; – Addressing the needs of the most vulnerable groups and the global increase of chronic diseases ; – Decoding the role of environment – including climate change and air quality – on health and developing mitigating measures; – Exploring the digital potential for health innovation and healthcare, including the building of a 'European health research and innovation cloud'; – Stimulating innovation in the European healthcare domain and industry by exploring the application of advanced technologies, improve the health of the workforce and promote regulatory science.

Hacia las convocatorias de SC1 2018-2019-2020 7 prioridades repartidas en 3 áreas Oportunidades convocatoria 2019 en topics BHC Area 1. Better health and care, economic growth and sustainable health systems (Topics BHC) 1. Personalised medicine 2. Innovative health and care industry 3. Infectious diseases and improving global health 4. Innovative health and care systems – Integration of care 5. Decoding the role of the environment for health and well-being Area 2. Digital transformation in health and care (Topics DTH) Area 3. Trusted digital solutions and cybersecurity in health and care (Topics TDS) Otras acciones. EIC: premios (en conv. 2020), Instrumento PYME, FTI, FET Open

Prioridad – Better Health and care, economic growth and sustainable health systems (I) Oportunidades convocatoria 2019 en topics BHC 1.1. Personalised Medicine  SC1-BHC-31-2019: Pilot actions to build the foundations of a human cell atlas (3-5 M € ; 3-5 projects – total 15 M € ) 1.2. Innovative health and care industry • SC1-BHC-07-2019: Regenerative medicine: from new insights to new applications (6-8M € ; 6-8 proyectos – total 50 M € ) • SC1-BHC-10-2019: Innovation Procurement: Next generation sequencing (NGS) for routine diagnosis (9-11 M € ; 3-4 proyectos – total 40 M € ) PCP funding scheme

SC1-BHC-31-2019: Pilot actions to build the foundations of a human cell atlas (I) Specific Challenge: Oportunidades convocatoria 2019 en topics BHC  To create molecular reference maps of all human cells .  To generate data and/or develop methods for in-depth, integrated molecular analysis and spatial resolution of single cells from complex biological systems such as human organs and tissues. Scope  Each pilot action should demonstrate the utility of an interdisciplinary technological/biological platform to generate and integrate standardised molecular, cellular, biochemical and other data sets, characterising single cells or their nuclear components, their interactions and/or spatial location in tissues from one human organ .  Platforms supporting analysis of tissues from more than one organ are also in scope. The primary focus should be on healthy tissues , though comparison between healthy and diseased tissues could be appropriate. Sex, age and ethnicity comparisons could also be considered.  The projects should have a duration of two years . To ensure coherence and communication between projects funded under this topic and with the HCA, the Commission will ensure an overall coordination mechanism between the projects.

SC1-BHC-31-2019: Pilot actions to build the foundations of a human cell atlas (II) Oportunidades convocatoria 2019 en topics BHC  The Commission considers proposals requesting a contribution from the EU of between EUR 3 and 5 million would allow for the specific challenge to be addressed appropriately. Nonetheless, this does not preclude submission and selection of proposals requesting other amounts. Expected Impact:  Timely contribution of project results to the HCA  Effective and sustainable biological and/or technological platforms.  Competitive and sustainable European role in HCA  Strong involvement of European technology SMEs  Laying the groundwork for improving diagnosis and treatment of disease

Oportunidades convocatoria 2019 en topics BHC SC1-BHC-07-2019: Regenerative medicine: from new insights to new applications

SC1-BHC-10-2019: Innovation Procurement: Next generation sequencing (NGS) for routine diagnosis Oportunidades convocatoria 2019 en topics BHC The objective is to implement NGS in routine diagnostics for personalised medicine and scale up demand-driven innovation for healthcare systems including organizational, economical, technical and clinical aspects. Expected Impact:  New NGS platforms and use of NGS tests in routine diagnostics for personalised  medicine.  Accepted new European standards and quality assurance schemes with respect to NGS.  Strengthening of implementation of personalised medicine and improved clinical decisions and health outcomes for the benefits of patients.  Contribution to the sustainability of healthcare systems.  Growth and benefit to the European industry, in particular SMEs. Type of Action: Pre-Commercial Procurement

Prioridad – Better Health and care, economic growth and sustainable health systems (II) Oportunidades convocatoria 2019 en topics BHC 1.3 Infectious diseases and improving global health • SC1-BHC-13-2019: Mining big data for early detection of infectious disease threats driven by climate change and other factors ( 12-15 M € ; 2-3 proyectos – total 30 M € ) • SC1-BHC-32-2019: Towards a next generation influenza vaccine to protect citizens worldwide – an EU-India collaboration (6-10 M € ; 1-2 proyectos – total 15 M € ) 1.5 Decoding the role of the environment for health and well-being  SC1-BHC-28-2019: The Human Exposome Project: a toolbox for assessing and addressing the impact of environment on health (8-12 M € ; 4-6 proyectos – total 50 M € )

SC1-BHC-13-2019: Mining big data for early detection of infectious disease threats driven by climate change and other factors (I) Oportunidades convocatoria 2019 en topics BHC Specific Challenge:  A range of factors is responsible for the (re-)emergence of infectious disease threats, including antimicrobial resistance.  The use of next generation sequencing combined with surveillance data, health registries and societal data from informal/non-traditional sources (e.g. social media) holds promise for improving individual and population health . Scope: It is expected that proposals develop: 1. the technology to allow the pooling, access, analysis and sharing of relevant data, including next generation sequencing; 2. the innovative bio-informatics and modelling methodologies that enable risk modelling and mapping; and 3. the analytical tools for early warning, risk assessment and monitoring of (re-) emerging infectious disease threats.