Introduction to the National Institutes of Health Presented By: - PowerPoint PPT Presentation

Introduction to the National Institutes of Health Presented By: Krista Montgomery Research Funding Manager, US & International Agencies Research Services Office, University of Toronto

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION Outline e  NIH Overview  Prior to Applying  The Application  Submission Process  Review Criteria & Process

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION NIH Ov H Overview • Agency of the U.S. Department of Health and Human Services • 27 Institutes and Centers • Operations are based in Bethesda, Maryland • $32.9 billion invested in FY2016 toward medical research • 80% of the NIH’s funding is awarded through 50,000 grants to institutions in and outside the US. • In FY2015, NIH awarded 502 grants totaling $246 million to Non-US Institutions--representing 1% of the total NIH funding awarded in FY 2015

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION NIH Organ anization Char n Chart

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION Missi ssion & & Goals s NIH’s mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability • to foster fundamental creative discoveries, innovative research strategies, and their applications as a basis for ultimately protecting and improving health; • to develop, maintain, and renew scientific human and physical resources that will ensure the nation’s capability to prevent disease ; • to expand the knowledge base in medical and associated sciences in order to enhance the nation’s economic well-being and ensure a continued high return on the public investment in research; and • to exemplify and promote the highest level of scientific integrity, public accountability, and social responsibility in the conduct of science.

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION Findi nding F Fundi unding www.grants.gov

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION Findi nding F Fundi unding http://grants.nih.gov/grants/funding/funding_program.htm

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION Findi nding F Fundi unding NIH LISTSERV https://grants.nih.gov/grants/guide/listserv.htm

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION Funding O Opportunity y Announcement

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION Typ ypes o of Funding An Announcements • Parent Announcement • Investigator initiated • IC-Specific Program Announcement (PA) • Investigator initiated • Specific research area relevant to IC • Request for Applications (RFA) • Specified amount of funding and # of awards • NIH requested research area

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION Reviewi ewing F FOA • Activity Code Type Grant, Page Limits, Dates and Funding Limits • Key Dates Due Dates, Start Dates, HIV Research • Eligibility Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. • Foreign Institutions Special Requirements • Funding Restrictions Limits/items cannot be funded • Other Submission Requirements & information Letter of Intent or Resource Sharing

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION Fundi unding ng Ac Activi vity Codes des Activity Code Duration Funding Characteristics Parent Mechanism Amount Announcement R03 1-2 yrs 50k Non-renewable, PA-13-304 PA-16-162 Small Research Grant Program most IC use PA-16-161 R21 1-2 yrs 275k Most ICs PA-13-303 Exploratory Development Non-renewable Research Grant R01 3-5 yrs No All ICs PA-13-302 PA-16-160 Research Project Grant Limit* Renewable Program U01 3-5 yrs No Involvement by ICs None - RFA Research Project Cooperative Limit* Renewable* Grants

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION Fundi unding Ac Activi vity Code Codes Activity Code Duration Funding Characteristics Parent Mechanism Amount Announcement R03 1-2 yrs 50k Non-renewable, PA-13-304 PA-16-162 Small Research Grant Program most IC use Provides funding to support short-term projects Limited to two years of funding • Direct costs up to $50,000 per year • Not renewable • Used by more than half of the NIH ICs •

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION Fundi unding Ac Activi vity Code Codes Activity Code Duration Funding Characteristics Parent Mechanism Amount Announcement PA-16-161 R21 1-2 yrs 275k Used by most ICs PA-13- Exploratory Development Non-renewable Research Grant Provides funding for new, exploratory and developmental research projects Limited to up to two years of funding • Combined budget for direct costs for the two year project period • may not exceed $275,000 Most ICs utilize •

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION Fundi unding Ac Activi vity Code Codes Activity Code Duration Funding Characteristics Parent Mechanism Amount Announcement PA-16-160 R01 3-5 yrs No Used by all ICs PA-13-302 Research Project Grant Limit* Renewable Program Provides funding to support a specified research project No specific dollar limit unless specified* • *$500K or more (direct costs) in any year requires prior approval Awarded for 3 – 5 years • All ICs use •

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION Fundi unding Ac Activi vity Code Codes Activity Code Duration Funding Characteristics Parent Mechanism Amount Announcement U01 3-5 yrs No Involvement by ICs None-RFA Research Project Cooperative Limit* Renewable* Grants Supports specific scientific area to accomplish specific research objectives. Used when programmatic involvement is expected by the awarding • Institute or Center No specific dollar limit unless specified • Cooperative agreement •

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION Prepar aring t g to Apply y  Determining Proposal a Good Fit  Involving Other Institutions  NIH FCOI Requirements  Finding Application Form & Instructions  Electronic Requirements

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION Is P Propo posal a a Good F d Fit?  RePORT  IC Research Priorities  Funding Announcement  Contact Program Officer

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION NIH Ma Match Ma Maker • Enter Abstract or Scientific Text • Similar projects funded • Breakdown of Activity Codes, IC and SRG

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION Invol olving A g Anot other I Institution on • Subawardee  Budget  Endorsement  Institutional Information  Administrative Requirements  Other (Biosketch, etc.) Start Early

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION Fina nancial Conflict o of Inter eres est • NIH Requirements • Responsibility of Applicants for Promoting Objectivity in Research for which PHS Funding is Sought (42 C.F.R. Part 50, Subpart F) • “Investigators”  Training  Financial Interests

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION Locating t g the A e Appl pplication 1. Download PDF Application & Instructions • Grants.gov • Form C or Form D (deadline May 25 or later) • Sign-up for e-mail notification 2. Application Submission System & Interface for Submission Tracking (ASSIST) • Web-based Application System • eRA Credentials

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION Elec ectron onic R Requirem emen ents • Supported Adobe Reader Version • Opening with unsupported version can corrupt application. • Adobe Converter • Application attachments • eRA Commons Account • Post Submission & Award System • All PD/PI listed on application need an Account • Institution to initiate account set-up

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION The Application

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION Application Components

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION Mandatory Application Sections • SF424 (R&R) Institution, Project Director and General Proposal Information • PHS 398 Research Plan Scientific Proposal & Other Attachments • PHS 398 Cover Page Supplement Project Director, Disclosure and Program Income

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION Mandatory Application Sections • R&R Senior Key Person Project Director and Other Key Person’s Information & CVs • R&R Other Project Information Ethics Assurances, Project Impact, Foreign Justification , Abstract, Narrative, Bibliography, Facilities, Equipment • R&R Project Performance Site Locations Locations of Project Performance

O FFICE OF THE V ICE -P RESIDENT , R ESEARCH AND I NNOVATION Optional Application Sections • PHS 398 Modular Budget DO NOT USE - US Institutions Only • R&R Budget Budget Details of Lead Institution • R&R Subaward Budget Attachments Individual Budgets for Subaward/Consortiums • PHS Assignment Request Form