DEEP-LEARNING APPROACHES TO VALIDATE FORMAL MODELS OF BIOLOGICAL - PowerPoint PPT Presentation

Aug 03, 2023 •760 likes •823 views

DEEP-LEARNING APPROACHES TO VALIDATE FORMAL MODELS OF BIOLOGICAL SYSTEMS Mahdi Behroozikhah, Dhranidar Dang, 11 0 1 0 1 0 1 1 0 1111 0 0 0 0 11 0 0 0 1 0 0 0 0 0 0 11 0 0 0 0 0 0 0 1 1111 0 0 0 0 Boolean Lab Debashis Sahoo 1 0 0 1 0 111

DEEP-LEARNING APPROACHES TO VALIDATE FORMAL MODELS OF BIOLOGICAL SYSTEMS Mahdi Behroozikhah, Dhranidar Dang, 11 0 1 0 1 0 1 1 0 1111 0 0 0 0 11 0 0 0 1 0 0 0 0 0 0 11 0 0 0 0 0 0 0 1 1111 0 0 0 0 Boolean Lab Debashis Sahoo 1 0 0 1 0 111 1 0 1 0 0 111 0 0 0 111 0 0 1111 0 0 0 1
Motivation ■ It It is h hard t to c create a a f formal m model o of f biological s systems b because t the w working principles a are o often unk unkno nown ■ Availability of high-throughput sequencing, generated massive d data in the context of biological systems ■ We developed a computational framework where we can start to build abstract formal model of a biological system
Overview ■ Gathered and analyzed hundreds studies ■ Introduced Boolean Model based on gene expression ■ Validated in colon tissue using deep learning
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