Can clinical trials address the realities of disease prevalence data? - PowerPoint PPT Presentation

Can clinical trials address the realities of disease prevalence data? 1

Examples of Variability - Considerations for Study Sample Relevant Co-morbidities Group differences Location “Place” Individual Factors American Journal of Stratifying key variables to identify important Public Health: April 2010, Vol. 100, No. subgroups of patients who might differentially S1: S72–S80 benefit from treatment 2

I f it were not for the great variability among individuals, medicine might as well be a science and not an art. —Sir William Osler, The Principles and Practice of Medicine 1892 3