Advancing Methods for Observational Studies September 19, 2020
Emily Evans • Has nothing to disclose. 2
Cynthia Girman Disclosures Rela latio ionship ip Company ny(ies es) Speakers Bureau Advisory Committee Mendel AI, Clinical Ink Board Membership International Society for Pharmacoepidemiology Consultancy – independent Adgero Biopharmaceutics, Avenue Therapeutics, Biovie, Boehringer- scientific consultant to healthcare Ingelheim, CytoSorbents, Inflexxion, Janssen Pharmaceuticals, Prana and biopharmaceutical companies Biotechnology, Regeneron Pharmaceuticals, Ritter Pharmaceuticals, Tremeau, Urovant Sciences Review Panel SPOR (Canada) Honorarium Ownership Interests Other Adjunct Professor, Dept of Epidemiology, UNC Gillings School of Global Public Health 3
Panelists Roee Gutman, PhD Associate Professor of Biostatistics Brown University Romain Neugebauer, PhD Research Scientist II Division of Research, Kaiser Permanente Northern California Scott Zeger, PhD John C. Malone Professor of Biostatistics and Medicine Johns Hopkins Bloomberg School of Public Health and Whiting School of Engineering Elizabeth A. Stuart, PhD Associate Dean for Education & Professor Johns Hopkins Bloomberg School of Public Health 4
PCORI’s Emphasis on Methodological Rigor • Methodology Committee • Charged with advancing the science & methods of patient-centered comparative effectiveness research • Development of PCORI’s Methodology Standards • Methodology Standards • Ensures that PCORI-funded studies are designed and conducted to generate strong, high-quality evidence • 65 standards in 16 topic areas • Methods Research Portfolio • Address limitations in existing approaches • Importance of dissemination & implementation to improve quality of future research 5
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