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Law Enforcement Sensitive Primer on Synthetic Opioids I/S Brian Dempsey 412-777-6945 brian.w.dempsey@usdoj.gov Law Enforcement Sensitive Sources ACOME - Overdose Free PA Website - Pennsylvania Opioid Overdose Reduction Technical -

  1. Law Enforcement Sensitive Primer on Synthetic Opioids I/S Brian Dempsey 412-777-6945 brian.w.dempsey@usdoj.gov

  2. Law Enforcement Sensitive Sources ACOME - Overdose Free PA Website - Pennsylvania Opioid Overdose Reduction Technical - Assistance Center (TAC) www.dea.gov - www.deadiversion.usdoj.gov - www.cdc.gov - www.drugabuse.gov - DEA Testimony Before the Subcommittee on - Crime, Terrorism, Homeland Security & Investigations on June 27, 2017

  3. Law Enforcement Sensitive Synthetic Designer Drugs New Psychoactive Substances (NPS)

  4. Law Enforcement Sensitive Synthetic Cannabinoids

  5. Law Enforcement Sensitive Synthetic Cannabinoids

  6. Law Enforcement Sensitive Synthetic Cathinone's

  7. Law Enforcement Sensitive Synthetic Hallucinogens (Phenethylamines)

  8. Law Enforcement Sensitive Synthetic Hallucinogens (Phenethylamines)

  9. Law Enforcement Sensitive Synthetic Opioids Fentanyl and its Analogues Opiates VS Opioids Opiates - Narcotic Analgesic derived from an Opium Poppy (Natural) - Not manufactured by chemical synthesis - Derived for the Opium Poppy Plant Opioids A synthetic narcotic that mimics the - natural poppy plant - Chemically manufactured narcotics - Narcotic analgesic that is not found in nature

  10. Law Enforcement Sensitive Synthetic Opioids Fentanyl and its Analogues

  11. Law Enforcement Sensitive Review of “NPS” New Psychoactive Substances (“NPS”) Synthetic Cannabinoids - Synthetic Cathinone - Synthetic Opioids - Synthetic Hallucinogens (Phenethylamines) -

  12. Law Enforcement Sensitive Fentanyl Citrate/Fentanyl HCL Schedule II

  13. Law Enforcement Sensitive Primer on Synthetic Opioids

  14. Law Enforcement Sensitive DEA National Forensic Laboratory Information System (NFLIS)

  15. Law Enforcement Sensitive DEA National Forensic Laboratory Information System (NFLIS) January 2013 – December 2016: 50,440 Fentanyl Reports 2013: 1,041 Fentanyl Reports 2016: 28,751 Fentanyl Reports CDC Morbidity & Mortality Weekly Report dated December 2016: The death rate from Synthetic Opioids (other than Methadone), which includes fentanyl, from 2014 to 2015, increased by 72.2% from 5,544 to 9,581.

  16. Law Enforcement Sensitive Primer on Synthetic Opioids “…(CDC) reported 33,091 deaths in 2015 which were the result of opioid overdoses alone. Of those deaths 9,581 were caused by synthetic opioids…”

  17. Law Enforcement Sensitive Primer on Synthetic Opioids Fentanyl & Fentanyl-Related Substances have been Identified in: Powder - Pill - Capsule - Liquid - (and on) Blotter Paper -

  18. Law Enforcement Sensitive Primer on Synthetic Opioids

  19. Law Enforcement Sensitive Primer on Synthetic Opioids On March 1, 2017, as a result of meeting with DEA, China agreed to regulate the following four fentanyl-related Substances under Chinese law: - Carfentanil - Furanyl Fentanyl - Acryl Fentanyl - Valeryl Fentanyl

  20. Law Enforcement Sensitive First Quarter 2017 Emerging Threat Report

  21. Law Enforcement Sensitive “Grey Death”

  22. Law Enforcement Sensitive Western Pennsylvania Seizures of Synthetic Opioids 2016 2017 Fentanyl Butyrylfentanyl 4-methoxybutyrylfentanyl Carfentanil Acetylfentanyl Cyclopropylfentanyl Butyrylfentanyl Furanyl fentanyl 3-methylfentanyl (cis and trans) Methoxyacetyl fentanyl Furanyl fentanyl Acrylfentanyl Para-fluoroisobutyryl fentanyl U-47700 U-47700

  23. Law Enforcement Sensitive DEA Seizure of 50 Kilograms Of ANPP on June 28, 2017

  24. Law Enforcement Sensitive The Drug Control Process Under The CSA

  25. Law Enforcement Sensitive The Drug Control Process Under The CSA 1985 – 2010 DEA utilized the CSA Authority a total of 13 times to control 25 substances. March 2011 – Present DEA utilized the CSA Authority a total of 14 times to control 46 synthetic designer drugs temporarily (emergency control) under Schedule I, including seven fentanyl analogues: Acetyl fentanyl Butyryl fentanyl Beta-hydroxythiofentanyl Furanyl fentanyl 4-fluoroisobutyryl fentanyl U-47700 Acryl Fentanyl

  26. Law Enforcement Sensitive Availability of Fentanyl Products Via the Internet

  27. Law Enforcement Sensitive Acetyl Fentanyl Internet Sales

  28. Law Enforcement Sensitive Acetyl Fentanyl Internet Sales

  29. Law Enforcement Sensitive Acetyl Fentanyl Internet Sales

  30. Law Enforcement Sensitive Availability of Fentanyl Products Via the Internet Product Form Description HCl powder, nasal spray, vape juice, edibles U-47700 (gummy bears) Synthetic opioid MethoxyAcetylFentanyl Powder, nasal spray Fentanyl analog Gabapentin Pill Pill that treats nerve pain Epitalon Injection Anti-aging drug Elavil (Amitriptyline) Pill Treats neuropathic pain and mental illnesses Selank Injection Nootropic mental stimulant

  31. Law Enforcement Sensitive Availability of Fentanyl Products Via the Internet 4-MEC a-PHP a-PVP AH-7921 Fentanyl powder (Attachment 2) Dibutylone crystal MDPV Furanyl fentanyl Pentedrone Methylone Crystals 25 I-NBOMe 2-FMA Hydrocodone Watson 853 Crystal Meth Soma Cocaine Vicodin Hydrocodone Watson 540 5F-AKB48 RoxiCodone AB-Chminaca Tramadol AM-2201 Actavis promethazine with codeine cough syrup Zolpidem 5fur 144 Methoxetamine AB-Pinaca Molly MDMA Pills PB-22 LSD pills Soma LSD powder Ketamine-Racemic LDS blotters Pure MDMA Diazepam Zopiclone

  32. Law Enforcement Sensitive Availability of Fentanyl Products Via the Internet

  33. Law Enforcement Sensitive Heroin 101 Heroin Stamp Bag Weighs Approximately .01 to .03 gms Heroin Stamp Bags Cost $5 to $15 Heroin “BUNDLE” Consists of 10 Individual Stamp Bags Heroin “BUNDLE” Costs $50 to $80 Heroin “BRICK” Consists of 50 Individual Stamp Bags Heroin “BRICKS” Cost $150 to $400 One (1) Gram of Heroin Sells for $150 One (1) Ounce of Heroin Sells for $2,000 to $3,000 One (1) Kilogram of Heroin Sells for $50,000 to $80,000

  34. Law Enforcement Sensitive Drug-Related Overdose Demographics & Drug Presence, Allegheny County, PA, 2016 Gender Race Age TOTAL OVERDOSE DEATHS 649* Drugs: Fentanyl 63.5% Alprazolam 19.1% Methadone 6.8% Heroin 50.8% Oxycodone 11.2% Hydrocodone 5.5% Cocaine 34.1% Clonazepam 8.3% Ethanol 29.7% Diazepam 6.8%

  35. Law Enforcement Sensitive 2016 4,642 DRUG RELATED OVERDOSE DEATHS This Number Represents a 37% increase in Overdose Deaths from 2015. This Number Established a Death Rate of 36.5 per 100,000 People. In 2016, approximately 13 people died of a drug-related overdose each day.

  36. Law Enforcement Sensitive 2016 4,642 DRUG RELATED OVERDOSE DEATHS In 2016, the presence of a prescription or illicit opioid was identified in 85% of the overdose deaths. Fentanyl and fentanyl-related substances were the most frequently identified (52% of deaths), exceeding heroin (45 % of deaths) for the first time.

  37. Law Enforcement Sensitive Fentanyl

  38. Law Enforcement Sensitive CARFENTANIL

  39. Law Enforcement Sensitive Fentanyl

  40. Law Enforcement Sensitive Primer on Synthetic Opioids

  41. Law Enforcement Sensitive Primer on Synthetic Opioids

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